Crystal engineering using the thiourea moiety

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Crystal structures of N,N'-(m-tolyl)thiourea and N,N'-(p-tolyl)thiourea.

C15H16N2S is monoclinic [orthorhombic], P2(1)/c [Pbcn]. Unit-cell dimensions at 293 K are a = 9.506(1), b = 7.629(1), c = 20.077(1)A, beta = 99.93(1) degrees, V= 1434.2(2)A(3), D(x) = 1.187 g/cm3, and Z = 4 [a = 11.806(2), b = 13.954(2), c = 8.466(1)A, V = 1394.7(3)A(3), D(x) = 1.221 g/cm3, and Z = 8]. The R value is 0.049 [0.045] for 1620 [1229] observed reflections. The dihedral angle between...

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Crystal structure of N-2-tolyl-N'-4-tolyl-thiourea.

lead and mercury poisoning in humans,1 we are currently working on the synthesis of a new series of chelating agents such as N-2-tolyl-N′-4-tolyl-thiourea (Fig. 1). In this paper, we present the crystal structure of (I). It is important to mention that there are only a few structure reports exclusively concerning substituted-thiourea derivatives, which may be due to the difficulty in preparing ...

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Crystal structure of N,N'-(p-chlorophenyl)thiourea.

mercury poisoning in humans,1 we are currently working on the synthesis of a new series of chelating agents, such as N,N′-(pchlorophenyl)thiourea (Fig. 1). In this paper, we present the crystal structure of (I). It is important to mention that there are a few structure reports exclusively concerning substitutedthiourea derivatives, which may be due to the difficulty in preparing crystals for X-...

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Synthesis, docking study and biological evaluation of some new thiourea derivatives bearing benzenesulfonamide moiety

BACKGROUND A series of novel N-(2, 6-dimethoxypyrimidin-4-yl)-4-(3-(aryl)thioureido) benzenesulfonamides 3a-t was synthesized by the addition of N-(2,6-dimethoxypyrimidin-4-yl)-4-isothiocyanatobenzenesulfonamide 2 to the appropriate aromatic amine. The structures of the synthesized compounds were inspired from the second line antituberculosis pro-drugs. RESULTS Most of the new compounds were ...

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Synthesis of novel aliphatic thiourea derivatives containing s-triazine moiety as potential antimicrobial agents

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ژورنال

عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography

سال: 2008

ISSN: 0108-7673

DOI: 10.1107/s0108767308097365